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Understanding the effects of genes on human traits

Recent technological developments in genomics have revealed a large number of genetic influences on common complex diseases, such as diabetes, asthma, cancer or schizophrenia. However, discovering a...

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Three subtypes of gastric cancer suggest different treatment approaches

Stomach cancer, one of the leading causes of cancer death worldwide, actually falls into three broad subtypes that respond differently to currently available therapies, according to researchers at...

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Results of the GIANT trial reported

According to a new study, genetic profiling of patients undergoing percutaneous coronary intervention (PCI) may help cardiology teams adjust treatment and improve ischemic outcomes for patients that do...

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Smart and personal: dietary advice

Tailoring people's diet to optimise their health and minimise their risk of disease, is a new scientific approach called personalised nutrition. But it remains a challenge.

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The nose knows in asthma

It has become increasingly clear in recent years that asthma comes in several variations, with different causes, different pathologies and different responses to therapy. These subtypes of asthma can...

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Research brings significant improvement in genetic analysis of tumours

Every tumour is unique and requires specific treatment. A thorough and complete analysis of the genetic activity in the tumour cells is necessary to determine the appropriate treatment. Researchers at...

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Researchers develop genetic profile of the Netherlands

In a large-scale research project under supervision of University Medical Center Groningen (UMCG) researchers have developed a genetic profile of the Netherlands. The researchers have mapped the DNA...

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Woman's genes give clue for unique liver cancer treatment

A 47-year-old American woman with intrahepatic cholangiocarcinoma (ICC) is the first person with her condition to receive a uniquely personalised treatment based on her genetic profile.

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Mining for clues: New DNA mapping project to discover the causes of MND...

The Irish arm of a new worldwide project which will dig deep into thousands of DNA profiles in order to discover the genetic causes of Motor Neurone Disease (MND) has been launched in Ireland by...

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A world first: Discovery of a personalized therapy for cardiovascular disease

Researchers at the Montreal Heart Institute announced today results showing that patients with cardiovascular disease and the appropriate genetic background benefit greatly from the new medication...

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Liquid biopsy provides real-time blood test for solid lung cancer tumors

In the rapidly changing world of molecular profiling for genetic diseases, cancer researchers are increasingly optimistic about the reality of a simple blood test to monitor and treat solid tumor cancers.

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Most cancer patients want tumor profiling, even if it reveals other genetic...

Most cancer patients would opt for tumor profiling even if the test revealed that they or their families were at risk for other genetic diseases, according to a Yale Cancer Center study. The findings...

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Pre-natal blood test study leads to 'unexpected' cancer diagnosis in three women

Researchers in Belgium trying to improve a blood test used to spot foetal disorders have found unexpected signs of cancer in three of the 4000 pregnant women on their study.

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Relapse, poor survival in leukemia linked to genetic mutations that persist...

For patients with an often-deadly form of leukemia, new research suggests that lingering cancer-related mutations - detected after initial treatment with chemotherapy - are associated with an increased...

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New drugs using only a computer, the internet and free online data

Pharmaceutical companies typically develop new drugs with thousands of staff and budgets that run into the billions of dollars. One estimate puts the cost of bringing a new drug to market at $2.6...

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Tapping crowd-sourced data unearths a trove of depression genes

Scientists have discovered 15 genome sites - the first ever - linked to depression in people of European ancestry. Many of these regions of depression-linked genetic variation turn out to be involved...

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Genetic mortality risk can be attenuated by lifestyle

(HealthDay)—Genetic variations correlate with mortality in the elderly, although their effect can be influenced by lifestyle behaviors, according to a study published online Nov. 2 in the Journal of...

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